Uruguayan Sign Language appears to be lexicostatistically distinct from Paraguayan Sign language ( Elizabeth Parks and Jason Parks 2015 ):8-9 and presumably from other sign languages as well.
Uruguayan Sign Language (7119-ugy) = Threatened (20 percent certain, based on the evidence available) (Ethnologue (2013) lists he vitality of Uruguayan Sign Language as: 5 (Developing).)
Endangered Languages Catalogue Project. Compiled by research teams at University of Hawai'i Mānoa and Institute for Language Information and Technology (LINGUIST List) at Eastern Michigan University
Glottolog
[ugy] at ISO 639-3
[ugy] at OLAC
[ugy] at IMTVault
Uruguayan Sign Language at Endangered Languages Project
Wikidata
Wikipedia